Rehabilitation protocols in neuropathic pain: bibliometric review / Protocolos de reabilitação na dor neuropática: revisão bibliométrica

ABSTRACT BACKGROUND AND OBJECTIVES: Neuropathic pain (NP) affects the afferent somatosensory pathways, generating various symptoms, however, there is difficulty in terms of diagnosis and in the formation of treatment protocols. There is a need to search the current literature for effective resources for the treatment of peripheral neuropathy in rehabilitation. The objective of this study was to describe reproducible assessment and treatment approaches capable of reducing NP. CONTENTS: Full articles produced between 2018 and 2022, found in the Pubmed, Scielo, Medline, Embase and Cochrane databases were included. Fifteen Boolean descriptors were used, and data were cross-referenced with the words "AND" or "OR". The selected articles went through the Methodi Ordinatio of classification and organization of studies. Eleven articles were selected and used in this review, two from 2018, five from 2020, and three from 2021. Regarding the type of study, five review articles, one case study, and six intervention studies were obtained. Of these 11 studies, only three used quality of life (QoL) indicators. Most studies used combined interventions, and in more than half of the publications transcranial direct current stimulation (tDCS) was present. The somatosensory rehabilitation method was able to redeem neuropathy through specific techniques. CONCLUSION: The implications of the neuropathic pain treatment in terms of QoL were left in the background by the bibliometric survey carried out. It is suggested that new studies could associate analgesia techniques with rehabilitation methods, including and measuring the effects on the QoL of these patients.

RESUMO JUSTIFICATIVA E OBJETIVOS: A dor neuropática (DN) acomete as vias somatossensoriais aferentes, gerando diversos sintomas, entretanto há dificuldades em termos de diagnóstico e na formação de protocolos de tratamento. Há a necessidade de buscar, na literatura atual, recursos eficazes para o tratamento da neuropatia periférica na área da reabilitação. O objetivo deste estudo foi descrever abordagens reprodutíveis de avaliação e tratamento capazes de diminuir a DN. CONTEÚDO: Foram incluídos artigos completos produzidos entre os anos de 2018 e 2022, encontrados nos bancos de dados Pubmed, Scielo, Medline, Embase e Cochrane. Foram usados 15 descritores booleanos, e os dados foram cruzados com as palavras "AND" ou "OR". Os artigos passaram pelo Methodi Ordinatio de classificação e organização de estudos. Foram selecionados e utilizados 11 artigos, sendo dois de 2018, cinco de 2020 e três de 2021. Acerca do tipo de estudo, foram obtidos cinco artigos de revisão, um estudo de caso e seis estudos de intervenção. Desses 11 estudos, apenas três utilizaram indicadores de qualidade de vida (QV). A maioria dos estudos utilizou intervenções combinadas, e em mais da metade das publicações a estimulação transcraniana por corrente contínua (ETCC) estava presente. O método de reabilitação somatossensorial foi capaz de redimir a neuropatia por meio de técnicas específicas. CONCLUSÃO: As implicações do tratamento da dor neuropática no quesito QV ficaram em segundo plano pelo levantamento bibliométrico realizado. Sugere-se que novos estudos possam associar técnicas de analgesia a métodos de reabilitação, incluindo e mensurando os efeitos sobre a QV desses pacientes.

Eficácia da reabilitação perineal combinada com biofeedback e diatermia por radiofrequência (RDF) em síndromes de dor funcional anorretal associadas à contração paradoxal dos músculos elevadores do ânus. Um estudo prospectivo / Effectiveness of perineal pelvis rehabilitation combined with biofeedback and radiofrequency diathermy (rdf) in anorectal functional pain syndromes associated with paradoxical contraction of the levator ani muscles. a prospective study

ABSTRACT Background: Anorectal functional pain syndrome, also called chronic proctalgia, represents a neglected clinical entity and often confused with other syndromes such as vulvodynia or acute proctalgia. It is a very often disabling disease with a consequent significant negative impact on the patient's quality of life. Chronic proctalgia, in many patients, is secondary to the paradoxical contraction of the pelvic floor and associated with a dissynergy between the thorax-abdomen and the pelvic floor. To improve symptoms in functional anorectal pain syndromes, various rehabilitation techniques are used with the aim of promoting relaxation of the pelvic floor; however, to improve defecatory dynamics in patients with levator ani syndrome, only biofeedback has shown efficacy in a randomized study. The aim of this work is to evaluate whether a rehabilitation protocol with manometric biofeedback and radiofrequency diathermy (mt100 Fremslife emotion Tecar) reduces pain and paradoxical contraction of the levator ani and improves the quality of life in patients with anorectal pain syndromes. functional. Methods: This was a prospective study on 30 patients (20 women and 10 men) with anorectal functional pain syndrome and paradoxical contraction of the pelvic floor enrolled at the UOC of General, Minimally Invasive, Oncological and Obesity Surgery of the AOU "Luigi Vanvitelli" of Naples, Italy, from September 2021 to May 2022. All patients were evaluated with a coloproctological specialist visit followed by anorectal manometry and evaluation of altered clinical physiatric parameters (Brusciano Score). The protocol consisted of 10 rehabilitation sessions of the pelvic floor once a week and lasting approximately 45 minutes. During the sessions the patients were subjected to diathermy / radiofrequency treatment (10 minutes) with a static resistive electrode on the diaphragm, during which they were required to breathe diaphragmatically and to become aware of the perineal muscles, under the supervision of a physiotherapist; followed by application of diathermy with static capacitive (5 minutes) and resistive (10 minutes) electrode at the lumbar level. This was followed by the use of manometric biofeedback (15 minutes of tonic / phasic exercises) in order to instruct the patient on the reflex mechanism to obtain a voluntary relaxation of the external anal sphincter. The variables evaluated were Pain (VAS 0-10) and the questionnaire on the impact of colorectal and anal pathologies on the quality of life (CRAIQ-7) at the beginning, after 3 months and at the end of the treatment. Results: After 10 weeks, the rehabilitation treatment combined with diathermy and manometric biofeedback proved effective in the short term with a reduction in the scores of the Vas scale and CRAIQ-7 questionnaire and an increase in the percentage of release of the anal muscles on anorectal manometry. Conclusion: The use of radiofrequency diathermy with a system of static electrodes associated with biofeedback represents a valid rehabilitation option for those patients suffering from anorectal functional pain syndrome because it reduces pain and paradoxical contraction of the levator ani and improves quality of life of the patient.

RESUMO Contexto: A síndrome de dor funcional anorretal, também conhecida como proctalgia crônica, representa uma entidade clínica negligenciada e frequentemente confundida com outras síndromes, como vulvodinia ou proctalgia aguda. Trata-se de uma doença frequentemente incapacitante, com um consequente impacto negativo significativo na qualidade de vida do paciente. A proctalgia crônica, em muitos pacientes, é secundária à contração paradoxal do assoalho pélvico e está associada a uma dissinergia entre o tórax-abdômen e o assoalho pélvico. Para melhorar os sintomas em síndromes de dor anorretal funcional, são utilizadas diversas técnicas de reabilitação com o objetivo de promover o relaxamento do assoalho pélvico. No entanto, para melhorar a dinâmica de evacuação em pacientes com síndrome do elevador do ânus, apenas o biofeedback demonstrou eficácia em um estudo randomizado. Objetivo: O objetivo deste trabalho é avaliar se um protocolo de reabilitação com biofeedback manométrico e diatermia por radiofrequência (mt100 Fremslife emotion Tecar) reduz a dor e a contração paradoxal do elevador do ânus e melhora a qualidade de vida em pacientes com síndromes de dor anorretal funcional. Métodos: Realizado estudo prospectivo com 30 pacientes (20 mulheres e 10 homens) com síndrome de dor anorretal funcional e contração paradoxal do assoalho pélvico inscritos na UOC de Cirurgia Geral, Minimamente Invasiva, Oncológica e de Obesidade da AOU "Luigi Vanvitelli" de Nápoles, Itália, de setembro de 2021 a maio de 2022. Todos os pacientes foram avaliados com uma consulta especializada em coloproctologia, seguida de manometria anorretal e avaliação dos parâmetros fisiátricos clínicos alterados (Escore de Brusciano). O protocolo consistiu em 10 sessões de reabilitação do assoalho pélvico, uma vez por semana, com duração aproximada de 45 minutos. Durante as sessões, os pacientes foram submetidos a tratamento de diatermia / radiofrequência (10 minutos) com um eletrodo resistivo estático no diafragma, durante o qual foram solicitados a respirar através do diafragma e a tomar consciência dos músculos perineais, sob a supervisão de um fisioterapeuta; seguido pela aplicação de diatermia com eletrodo capacitivo estático (5 minutos) e resistivo (10 minutos) no nível lombar. Isso foi seguido pelo uso de biofeedback manométrico (15 minutos de exercícios tônicos /fásicos) com o objetivo de instruir o paciente sobre o mecanismo reflexo para obter um relaxamento voluntário do esfíncter anal externo. As variáveis avaliadas foram Dor (EVA 0-10) e o questionário sobre o impacto das patologias colorretais e anais na qualidade de vida (CRAIQ-7) no início, após 3 meses e no final do tratamento. Resultados: Após 10 semanas, o tratamento de reabilitação combinado com diatermia e biofeedback manométrico mostrou-se eficaz a curto prazo, com uma redução nos escores da escala VAS e do questionário CRAIQ-7, e um aumento na porcentagem de relaxamento dos músculos anais na manometria anorretal. Conclusão: O uso de diatermia por radiofrequência com um sistema de eletrodos estáticos associado ao biofeedback representa uma opção de reabilitação válida para pacientes que sofrem com a síndrome de dor anorretal funcional, pois reduz a dor e a contração paradoxal do elevador do ânus, melhorando a qualidade de vida do paciente.

Intervention effect of Qufeng Gutong Cataplasm on myofascial pain syndrome in rats and its mechanism / 中国中药杂志

This paper aims to investigate the intervention effect of Qufeng Gutong Cataplasm(QFGT) on myofascial pain syndrome(MPS) in rats and to preliminarily explain its mechanism from the perspective of improving muscle inflammation and pain. Male SD rats were divided into 6 groups, namely normal group, model group, positive control drug(Huoxue Zhitong Ointment, HXZT) group, and low, medium, and high-dose QFGT groups(75, 150, and 300 mg·d~(-1)). The rat model of MPS was established by striking combined with centrifugation for 8 weeks, during which QFGT and HXZT were used for corresponding intervention. Standard VonFrey fiber was used to evaluate the mechanical pain threshold, and acetone was used to detect the cold pain threshold. The electrophysiological activity of muscle at trigger point was detected, and the electromuscular analysis of trigger point was performed. CatWalk gait analyzer was used to detect pain-induced gait adaptation changes. The hematoxylin-eosin(HE) staining was used to observe the pathological changes in muscle and skin tissues at the trigger point of rats. Immunohistochemistry was used to detect the expression of capsaicin receptor transient receptor potential vanilloid 1(TRPV1) in muscle tissues and interleukin(IL)-33 in skin tissues at the trigger point. The protein expression levels of TRPV1, protein kinase B(Akt), phosphorylated protein kinase B(p-Akt), IL-1β, and tumor necrosis factor-α(TNF-α) in muscle tissues at the trigger point were detected by Western blot. The results showed that as compared with the model group, the mechanical pain threshold and cold pain threshold of rats in other groups were increased after treatment with QFGT. The spontaneous electromyography(EMG) activity was observed in the model group, but QFGT alleviated the EMG activity in a dose-dependent manner. Gait analysis showed that standing duration, average intensity, swing speed, maximum contact point, maximum contact area, paw print length, paw print width, and paw print area were significantly improved in all QFGT groups. Pathological results showed that the disorder of muscle arrangement at the trigger point was decreased, muscle fiber adhesion and atrophy were reduced, and inflammatory cell infiltration was alleviated after treatment with QFGT. In addition, QFGT and HXZT both inhibited the protein expression of TRPV1, PI3K, Akt, p-Akt, IL-1β, and TNF-α in the muscle tissues of rats with MPS. However, there was no significant difference in the pathological structure and expression of IL-33 in the treated skin as compared with the normal group. The related results have proved that QFGT can inhibit the release of inflammatory factors by inhibiting the TRPV1/PI3K/Akt signaling pathway in the muscle trigger point of rats with MPS and finally attenuate the atrophy and adhesion of local muscles and inflammatory infiltration, thereby relieving the muscle pain of rats with MPS, and local administration has no skin irritation.

Effect of Electroacupuncture at Proximal and Distal Acupoints on Pain-inducing Substances， Macrophages and Related Inflammatory Factors in Myofascial Pain Syndrome Model Rats / 中医杂志

ObjectiveTo explore the possible peripheral analgesic mechanism of electroacupuncture （EA） at promimal and distal acupoints in treatment of myofascial pain syndrome （MPS）. MethodsTwenty-four SD rats were randomly divided into blank group， model group， proximal group， and distal group， with six rats in each group. MPS model was prepared by “strike combined with centrifugal exercise” in all groups except for the blank group. After modeling， the rats in the proximal group received EA at the local myofascial trigger points （MTrPs）， namely the Ashi points， with dilatational waves of frequency of 2/100 HZ and voltage of 2-4 V， current intensity depending on a slight trembling of the left lower limbs， once a day， 15min each time，for 14 days. The rats in the distal group received EA at “Yanglingquan” （GB 34） and “Yinlingquan” （SP 9）， with the same operations as the proximal group. The rats in the blank group and the model group were only grasped and hedged， without other interventions. After intervention， the paw withdrawl mechanical threshold （PWMT） was measured， and variability between the left and right hind paws was calculated. Musculoskeletal ultrasound imaging and electromyography monitoring were performed on the left lower extremity vastus medialis. The morphological changes of vastus medialis muscle of the left lower extremity were observed by HE staining. The positive expression of substance P （SP）， calcitonin gene-related peptide （CGRP）， CD68 and CD206 in muscle tissue was detected by immunohistochemistry. Abdominal aortic serum interleukin-1β （IL-1β）， interleukin-6 （IL-6）， tumor necrosis factor-α （TNF-α）， interleukin-10 （IL-10）， and interleukin-8 （interleukin-8） were detected by ELISA. ResultsCompared to those in the blank group， the fibers of the vastus medial muscle of the rats in the model group were broken and distorted with thickness in variation， and the myofascia was broken， with fibrillation potential， enlarged muscle cells， inward moved nucleus， and widened muscle space； the variability of PWMT between the left and right hind paws significantly increased， as well as the levels of SP， CGRP， CD68， and CD206 in the vastus medialis muscle （P＜0.01）， and the serum IL-8 and TNF-αlevels were significantly elevated （P＜0.05 or P＜0.01）. Compared to those in the model group， the muscle fibers in the proximal and distal group were complete in shape and arranged in an orderly manner， with continued non-broken myofascia， regular shape of muscle cells， and significantly reduced level of IL-8 （P＜0.01）； the amplitude and frequency of spontaneous discharge in the proximal group significantly decreased， as well as the variability of PWMT between the left and right hind paws， and the levels of SP， CGRP， and CD68 in the vastus medialis muscle， while the CD206 level increased significantly （P＜0.05 or P＜0.01 ）； there was complex discharges in the distal group， with significantly decreased level of CD68 in the vastus medialis muscle and increased level of CD206 （P＜0.01）. Compared to the proximal group， the level of IL-8 in the distal group was significantly higher （P＜0.05）. ConclusionsEA at proximal acupoints can significantly improve the pain threshold and local muscle tissue morpho-logy in rats， and its mechanism may be related to reducing the levels of pain-causing substances and related inflammatory factors and promoting the polarization of macrophages. The analgesic effect of EA at distal acupoints is not obvious， and the mechanism is still unclear.

Odinofonía: una actualización clínica

Introducción: En la actualidad, la odinofonía es considerada como un síntoma más dentro de los desórdenes de la voz y, por lo mismo, su estudio ha tenido una relevancia menor en comparación a la investigación del dolor expresado en otras regiones del cuerpo humano. Objetivo: Actualizar el concepto de odinofonía, según los últimos hallazgos que explican su etiología, evaluación y manejo terapéutico. Método: Se buscaron trabajos en las bases de datos PubMed, Scopus, ScienceDirect y SciELO. Se seleccionaron artículos según diversos criterios, que incluyeron la fecha de publicación, el diseño y el objetivo. Resultados: La etiología de la odinofonía incluye, según criterios de intensidad y cronicidad del dolor, a la odinofonía primaria y secundaria. La evaluación de la odinofonía comprende una detallada entrevista clínica; la identificación, mediante escalas e índices, de su frecuencia, intensidad y duración; y la aplicación de herramientas como la algometría, para reconocer el grado de sensibilidad de los tejidos afectados. La intervención de la odinofonía depende de su naturaleza (primaria o secundaria) y, en general, incluye al abordaje educativo, sintomático, biomecánico y psicosocial. Conclusión: La literatura actual posiciona a la odinofonía como una condición compleja, cuya etiología, evaluación e intervención aún carecen de total comprensión.

Introduction: At present, odynophonia is considered one more symptom within voice disorders and, therefore, its study has had less relevance if compared to the research of pain expressed in other regions of the human body. Objective: To update the concept of odynophonia, according to the latest findings that explain its etiology, evaluation and therapeutic management. Methodology: The databases PubMed, Scopus, ScienceDirect, and SciELO were searched. Articles were selected according to various criteria, including date of publication, design and objective. Results: The etiology of odynophonia, according to criteria of intensity and chronicity of pain, includes primary and secondary odynophonia. The evaluation of odynophonia entails a detailed clinical interview; the identification of its frequency, intensity and duration using scales and indexes; and the application of tools such as algometry, to recognize the degree of sensitivity of the affected tissues. The intervention of odynophonia depends on its nature (primary or secondary) and, in general, includes educational, symptomatic, biomechanical and psychosocial approaches. Conclusion: Current literature positions odynophonia as a complex condition, whose etiology, evaluation, and intervention are still not fully understood.

Influence of walking and running on patellofemoral pain / Influência da caminhada e da corrida na dor femoropatelar

Abstract Due to the ease of its practice, walking / running can be performed in such a way that there is no adequate control or monitoring, resulting in the appearance of injuries, highlighting patellofemoral pain. Thus, the present study aimed to verify the levels of patellofemoral pain in walk / run practitioners. The sample consisted of 318 individuals, selected in a non-probabilistic manner, for convenience and adherence, including over 18 years old, both sexes, living in the state of Pernambuco, Brazil, who practiced walking / running. Data collection was performed using an online questionnaire on the google platform. Participants who agreed to participate answered a sociodemographic questionnaire, the International Physical Activity Questionnaire (IPAQ) and a subscale of patellofemoral pain and osteoarthritis of the KOOS questionnaire. Data were presented using descriptive statistics (mean and standard deviation), submitted to inferential statistics using Student's t test, ANOVA with Bonferroni's post hoc to show the effect of comparisons, considering a significance level of 5% (p <0.05). There were no significant differences between the variables analyzed (p = 0.599; ES = 0.06), suggesting that there is no difference in patellofemoral pain in practitioners of walking / running between the sexes and different levels of physical activity; research with larger samples and monitoring of more variables, in the search for more assertive results, should be carried out.

Resumo Pela facilidade de sua prática, a caminhada / corrida pode ser realizada de forma que não haja controle ou monitoramento adequado, resultando no aparecimento de lesões, destacando a dor femoropatelar. Assim, o presente estudo teve como objetivo verificar os níveis de dor femoropatelar em praticantes de caminhada / corrida. A amostra foi composta por 318 indivíduos, selecionados de forma não probabilística, por conveniência e adesão, incluindo maiores de 18 anos, ambos os sexos, residentes no estado de Pernambuco, Brasil, que praticavam caminhada / corrida. A coleta de dados foi realizada por meio de questionário online na plataforma google. Os participantes que aceitaram participar responderam a um questionário sociodemográfico, o Questionário Internacional de Atividade Física (IPAQ) e subescala de dor patelofemoral e osteoartrite do questionário KOOS. Os dados foram apresentados através da estatística descritiva (média e desvio padrão), submetidos à estatística inferencial por meio do teste t de Student, ANOVA com post hoc de Bonferroni para mostrar o efeito das comparações, considerando nível de significância de 5% (p<0,05). Não foi observada diferenças significantes entre as variáveis analisadas (p = 0,599), sugerindo que não há diferença no dor femoropatelar em praticantes de caminhada / corrida entre os sexos e diferentes níveis de atividade física; pesquisas com amostras maiores e monitoramento de mais variáveis, na busca por resultados mais assertivos, devem ser realizadas.

Acupuncture for chronic prostatitis/chronic pelvic pain syndrome: a randomized controlled trial / 中国针灸

OBJECTIVE@#To observe the short-term efficacy, long-term efficacy and safety of acupuncture for chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS).@*METHODS@#Forty-two patients with CP/CPPS were randomly divided into an acupuncture group (21 cases, 1 case dropped off) and a sham acupuncture group (21 cases). The patients in the acupuncture group were treated with acupuncture at bilateral Zhongliao (BL 33), Huiyang (BL 35), Shenshu (BL 23) and Sanyinjiao (SP 6); the needling depth of Zhongliao (BL 33) and Huiyang (BL 35) was 60 to 80 mm, while Shenshu (BL 23) and Sanyinjiao (SP 6) was directly punctured of 30 mm. The patients in the sham acupuncture group were treated with acupuncture at non-acupoints, including points 2 cm next to Shenshu (BL 23), Zhongliao (BL 33) and Huiyang (BL 35), and the midpoint of the connecting line between the spleen meridian and the kidney meridian. All the non-acupoints were treated with directly puncture of 2 to 3 mm. The needles were left for 30 min in both groups, once every other day in the first four weeks, three times a week, and twice a week in the next four weeks, totally 20 treatments. Before treatment, after treatment and in follow-up of 24 weeks after treatment completion, the National Institutes of Health-chronic prostatitis symptom index (NIH-CPSI) score and urinary flow rate were observed in both groups; the clinical efficacy and safety were evaluated.@*RESULTS@#Compared with those before treatment, the pain and discomfort scores, urination symptoms scores, quality of life scores and total scores of NIH-CPSI in both groups were reduced after treatment in the two groups (P<0.01), while each item score and total score of NIH-CPSI in the acupuncture group were reduced in follow-up (P<0.01, P<0.05). After treatment and in follow-up, each item score and total score of NIH-CPSI in the acupuncture group were lower than those in the sham acupuncture group (P<0.05, P<0.01). After treatment, the maximum and average urinary flow rates in the acupuncture group were higher than those before treatment (P<0.05), and the average urinary flow rate in the acupuncture group was higher than that in the sham acupuncture group (P<0.05). The total effective rate was 75.0% (15/20) in the acupuncture group, which was higher than 42.9% (9/21) in the sham acupuncture group (P<0.05). No significant adverse reactions were observed in the two groups, and there was no significant difference in the incidence of adverse reactions between the two groups (P>0.05).@*CONCLUSION@#Acupuncture could effectively alleviate the clinical symptoms, improve quality of life, and has a sustained, safe and reliable therapeutic effect in patients with CP/CPPS.

Initial study on a comprehensive strategy for female patients with bladder pain syndrome / 现代泌尿外科杂志

【Objective】 To explore the efficacy of a comprehensive treatment strategy of bladder hydrodistension, transurethral resection of bladder lesions and triple drug instillation in patients with painful bladder syndrome (BPS). 【Methods】 A total of 15 female BPS patients treated during Jan.2020 and Oct.2021 were enrolled. All patients received bladder hydrodistension and transurethral resection. After operation, intravesical instillation of a triple-drug mixture (2% lidocaine hydrochloride 20 mL, heparin sodium 25 000 U, and dexamethasone 10 mg) was administered once a day for 5 days, and then once per week for 4 weeks. The Visual Analogue Scale (VAS) score, quality of sexual life, health-related quality of life, and self-rating anxiety scale score were compared before treatment and 1, 4 and 12 weeks after treatment. The complications were recorded. 【Results】 All patients completed the treatment. Of 14 patients, the VAS score and self-rating anxiety scale score were lower in week 1, 4 and 12 after treatment, while the health-related quality of life score increased. One patient’s symptoms remained unchanged. The VAS score decreased from (5.47±1.81) to (1.87±1.51) (P<0.05), and the self-rating anxiety scale score decreased from (18.13±8.64) to (6.33±8.22) (P<0.05). The score of health-related quality of life increased from (24.47±5.41) to (31.53±6.49) (P<0.05). 【Conclusion】 The comprehensive strategy is effective in the treatment of bladder pain syndrome, which can relieve pain symptoms and improve patients’ quality of life.

Effects of psychological intervention on NIH-CPSI score of CP/CPPS patients in Ngari Prefecture of Tibet / 现代泌尿外科杂志

【Objective】 To investigate the psychological status of patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), and to analyze the effects of anxiety on the total National Institute of Health Chronic Prostatitis Symptom Index (NIH-CPSI) in patients in Ngari Prefecture of Tibet. 【Methods】 CP/CPPS patients treated during Oct.2019 and Oct.2021 were involved and divided into anxiety group and non-anxiety group. The non-anxiety group received routine drug treatment, while the anxiety group received drugs and psychological intervention. 【Results】 A total of 117 patients were involved, including 68 in the anxiety group and 49 in the non-anxiety group. There were no statistical differences between the two groups in terms of age, body mass index (BMI), marital status, smoking history, and education level (P>0.05). The total NIH-CPSI score in the anxiety group (18.53±3.47) was higher than that in non-anxiety group (15.67±3.33), which was mainly manifested by the increase of pain and decrease of quality of life scores. Further stratification of anxiety level revealed that quality of life score and total NIH-CPSI score increased as anxiety symptoms worsened. After drug treatment, pain and urination symptoms were improved in the non-anxiety group, but the quality of life score and total NIH-CPSI score did not change significantly. After psychological intervention, the anxiety group had lower total NIH-CPSI score and other scores. 【Conclusion】 It is not uncommon for CP/CPPS patients to have a comorbidity of anxiety. The increase in the total NIH-CPSI score is caused by the increase of pain score and decrease of quality of life score. Active psychological intervention can improve anxiety, urinary symptoms, pain symptoms and quality of life.

Latest advances in the diagnosis and treatment of interstitial cystitis/bladder pain syndrome / 现代泌尿外科杂志

Interstitial cystitis/bladder pain syndrome (IC/BPS) is characterized by pain, oppressing sensation, or discomfort associated with the bladder, accompanied by lower urinary tract symptoms, lasting for more than 6 weeks (or 6 months). Since IC/BPS was first reported, its diagnosis and treatment have been a challenge to clinicians. This article will review its classification and phenotype, fundamental research, imaging, symptom score, cystoscopy, treatment and potential therapeutic targets.

Mechanism of Osteoking in Improving Energy Metabolism in Rats with Myofascial Pain Syndrome Based on cAMP/PKA/PGC1α Signaling Pathway / 中国实验方剂学杂志

ObjectiveFrom the perspective of energy metabolism， the mechanism of Osteoking （OK） in the treatment of myofascial pain syndrome （MPS） was revealed through systems biology prediction combined with holistic animal experimental validation methods. MethodFirstly， the key targets of MPS and their related molecular mechanisms were predicted by the systems biology method， and the core network targets were screened. Then， the network-predicted targets were verified by animal experiments. Specifically， 60 SD rats were randomly divided into normal group， model group， low， medium， and high dose OK groups （0.66， 1.31， 2.63 mL·kg-1）， and positive celecoxib group （21 mg·kg-1）. The MPS model was established by beating combined with a centrifugal exercise method for eight weeks. Except for two days after modeling， the intervention of OK or celecoxib was performed. After the completion of the model， the drug was administered for two weeks. The histopathological changes of trigger point muscle tissue were observed by hematoxylin-eosin staining. The content/activity of Na-K-ATP enzyme （Na+-K+-ATPase）， Ca2+ pump （Ca2+ATPase）， Ca2+， lactate dehydrogenase （LDH）， glutathione （GSH）， malondialal （MDA）， superoxide dismutase （SOD）， cyclic adenosine phosphate （cAMP）， and protein kinase A （PKA） in serum and/or trigger point muscle tissue in MPS rats was detected by enzyme-linked immunosorbent assay. Protein expression levels of PKA and the peroxisome proliferator-activated receptor γ coactivator 1α （PGC1α） in MPS rats were detected by immunohistochemistry. The protein expression levels of PKA， PGC1α， and mitochondrial transcription factor A （TFAM） in MPS rats were detected by Western blot. ResultThe network prediction results suggest that OK acts on the key target of energy metabolism related to the occurrence and development of MPS and may participate in the activation of the cAMP/PKA/PGC1α signaling pathway. The experimental validation results show that compared with the normal group， contracture nodules and disordered arrangement of muscle fibers appear in the trigger point muscle tissue of MPS rats. Na+-K+-ATPase， Ca2+ATPase， SOD activity， Ca2+， and GSH contents in serum and/or trigger point muscle tissue are significantly decreased （P<0.01）. Both LDH activity and MDA contents are significantly increased （P<0.01）， and the protein expression levels of cAMP， PKA， PGC1α， and TFAM are significantly decreased （P<0.01）. Compared with the model group， OK improves the histopathological morphology of trigger point muscle fibers in MPS rats， and after the intervention of OK， Na+-K+-ATPase， Ca2+ATPase， SOD activity， Ca2+， and GSH contents in serum and/or trigger point muscle tissue in MPS rats are significantly increased （P<0.05， P<0.01）. LDH activity and MDA contents are significantly reduced （P<0.05， P<0.01）. The protein expression levels of cAMP， PKA， PGC1α， and TFAM are significantly increased （P<0.05， P<0.01）. ConclusionThe mechanism of OK's intervention in MPS rats may be related to its effective activation of the cAMP/PKA/PGC1α signaling pathway， thus promoting mitochondrial energy metabolism and trigger point muscle fiber damage repair in muscle cells.

Intervention of Osteoking in Rats with Myofascial Pain Syndrome / 中国实验方剂学杂志

ObjectiveTo clarify the intervention effect of Osteoking （OK） in rats with myofascial pain syndrome （MPS） and preliminarily explore the pharmacological mechanism of OK in relieving chronic pain from the perspective of anti-inflammatory disease. MethodThe 60 SD rats were divided into normal group， model group， low， medium， and high dose OK groups （0.66， 1.31， 2.63 mL·kg-1）， and positive celecoxib group （21 mg·kg-1）. The MPS rat model was established by beating combined with the centrifugal exercise method， and the OK and celecoxib were given at the same time. SMALGO paw pressure pain manometer detected the shock pain point tenderness threshold of rats， and the Von-Frey needle and acetone stimulation method detected the mechanical hyperalgesia threshold and cold hyperalgesia stimulation response respectively. Eight weeks and 10 weeks after modeling， the spontaneous discharge state and convulsion response of MPS rats were determined by electromyograph （EMG） instrument. The gait changes of MPS rats were detected using a CatWalk gait analyzer. The expression levels of interleukin-1 β （IL-1β）， tumor necrosis factor-α （TNF-α）， substance P （SP）， and bradykinin （BK） were measured by enzyme-linked immunosorbent assay （ELISA）. The protein expression levels of nuclear transcription factor-κB （NF-κB） inhibiting protein α （IκBα）， phosphorylates （p）- IκBα， NF-κB p65， and p-NF-κB p65 were detected in MPS rats by Western blot. The positive expression of p-NF-κB p65 was detected by immunofluorescence. ResultCompared with the normal group， the model group shows 100% positive rates for EMG signal and local convulsions response at both the 8th and 10th weeks. The tenderness threshold and mechanical hyperalgesia threshold are significantly reduced. Cold hyperalgesia score is significantly increased， and gait is abnormal. The expression levels of serum and trigger points IL-1β， TNF-α， SP， BK， p-IκBα， and p-NF-κB p65， as well as the positive expression intensity of p-NF-κB p65 are significantly increased （P<0.01）. Compared with the model group， the positive rate of EMG detection and local convulsion response is significantly reduced in the medium and high dose OK groups （P<0.05）. The tenderness threshold and mechanical hyperalgesia threshold increase significantly in the medium and high dose OK groups， and the cold hyperalgesia score is significantly reduced in the high dose OK group （P<0.01）. The standing time， swing time， and walking period are significantly increased. The swing speed， maximum contact area， and maximum contact intensity are significantly decreased in the high dose OK group （P<0.05）. Moreover， the protein expression levels of p-IκBα/IκBα and p-NF-κB p65/NF-κB p65 are significantly reduced in the medium and high dose OK groups （P<0.05，P<0.01）. The positive expression intensity of p-NF-κB p65 is significantly decreased in the high dose OK group （P<0.01）. ConclusionThe mechanism of OK in relieving the pain in trigger points of MPS and improving gait abnormalities is related to the downregulation of the NF-κB p65 inflammatory signaling pathway to reduce the expression of inflammatory factors and pain mediators in blood and trigger point tissue.

Prevalence of chondromalacia patella according to patella type and patellofemoral geometry: a retrospective study

Abstract BACKGROUND: The relationships between the morphometric structure of the patellofemoral joint, patella type and chondromalacia patella are still a matter of debate. OBJECTIVE: To identify the prevalence of chondromalacia patella by determining the patella type and making patellofemoral morphometric measurements. DESIGN AND SETTING: Retrospective cohort study in an orthopedics and traumatology clinic in Turkey, conducted between June 2017 and November 2019. METHODS: This study involved 562 knees of 522 patients with anterior knee pain (246 males and 316 females; mean age 46.59 years). The patients were grouped according to presence of chondromalacia patella (group I) or absence of chondromalacia patella (group II). The patella type, lateral trochlear inclination, medial trochlear inclination, trochlear angle, sulcus angle, patellar tilt and Insall-Salvati index were assessed. Group comparisons were made using chi-square tests or Student t tests. The r value was used to determine the magnitude of relationships between pairs of variables. RESULTS: Among the 562 knees evaluated, 265 (50.71%) presented type I patella, 195 (36.7%) type II, 100 (12.3%) type III and 2 (0.3%) type IV. Group I consisted of 448 knees and group II consisted of 114 knees. Significant differences were found between the groups in terms of age, gender, patella type and lateral inclination angles (P < 0.05). CONCLUSION: Detecting the patella type and making lateral inclination measurements in patients with anterior knee pain are of great importance for diagnosing suspected chondromalacia patella, particularly in the early degenerative period.

Prevalencia de dispepsia funcional en adolescentes cubanos / Prevalence of Functional Dyspepsia in Cuban Adolescents

Resumen Introducción: los trastornos digestivos funcionales son frecuentes en niños; sin embargo, hay escasos datos sobre la dispepsia funcional (DF) en adolescentes cubanos. Objetivo: determinar la prevalencia de DF en adolescentes cubanos y sus posibles asociaciones. Metodología: se usó el cuestionario para síntomas digestivos pediátricos de Roma IV en español para identificar la presencia de DF en adolescentes de 3 centros escolares de La Habana, Cuba. Se tuvieron en cuenta variables sociodemográficas, personales, familiares, clínicas y epidemiológicas. Resultados: de los 318 adolescentes que participaron en el estudio, 11 adolescentes (3,5 %) de 11,4 ± 1,2 años de edad, 81,8 % de sexo femenino, presentaron DF. La DF fue más frecuente en el sexo femenino (odds ratio [OR]: 5,33; intervalo de confianza [IC] 95 %: 1,06-51,45; p = 0,019). El síndrome de dificultad posprandial (SDP) fue mayor que el síndrome de dolor epigástrico (SDE) en una proporción 1,8:1. En el 63,6 % se presentó superposición entre DF y estreñimiento funcional. Hubo predominio de DF en los niños con padres separados/divorciados (OR: 4,74; IC 95 %: 1,09-28,31; p = 0,014). Conclusión: la DF es más común en adolescentes femeninas, el SDP es el subtipo más frecuente y su presencia está asociada con padres separados/divorciados.

Abstract Introduction: functional gastrointestinal disorders (FGID) are common in children. However, data on functional dyspepsia (FD) in Cuban adolescents is scarce. Objective: to determine the prevalence of FD in Cuban adolescents and their possible associations. Methodology: the questionnaire for pediatric digestive symptoms of Rome IV was used in Spanish to identify the presence of DF in adolescents from 3 schools in La Havana, Cuba. Sociodemographic, personal, family, clinical, and epidemiological variables were considered. Results: of the 318 adolescents who participated in the study, 11 (3.5%) aged 11.4 ± 1.2 years, 81.8% female, presented FD. Functional dyspepsia was more frequent in females (odds ratio [OR]: 5.33; 95% confidence interval [CI]: 1.06-51.45; p = 0.019). The postprandial distress syndrome (PDS) was higher than the epigastric pain syndrome (SDE) by a 1.8:1 ratio. There was an overlap between DF and functional constipation in 63.6% of the patients. There was an FD predominance in children with separated or divorced parents (OR: 4.74; 95% CI: 1.09-28.31; p = 0.014). Conclusion: functional dyspepsia is most common in female adolescents, PSD is the most frequent subtype, and its presence is associated with separated or divorced parents.

Idiopathic musculoskeletal pain, musculoskeletal pain syndromes, and use of electronic devices in adolescents with asthma

Abstract Objective: To evaluate idiopathic musculoskeletal pain, musculoskeletal pain syndromes, and use of electronic devices in adolescents with asthma and healthy controls. Methods: Cross-sectional study was conducted on 150 asthmatic adolescents and 300 controls. Adolescents completed a self-administered questionnaire regarding painful symptoms, use of electronic devices, and physical activity. Seven musculoskeletal pain syndromes were evaluated, and Asthma Control Test (ACT) was assessed. Results: Musculoskeletal pain (42% vs. 61%, p = 0.0002) and musculoskeletal pain syndromes (2.7% vs. 15.7%, p = 0.0006) were significantly lower in asthmatic adolescents than in controls. The frequency of pain in the hands and wrists was reduced in asthmatic than in controls (12.6% vs. 31.1%, p = 0.004), in addition to cell phone use (80% vs. 93%, p < 0.0001), simultaneous use of at least two electronic media (47% vs. 91%, p < 0.0001), myofascial syndrome (0% vs. 7.1%, p = 0.043), and tendinitis (0% vs. 9.2%, p = 0.008). Logistic regression analysis, including asthma with musculoskeletal pain as the dependent variable, and female sex, ACT > 20, simultaneous use of at least two electronic devices, cell phone use, and weekends and weekdays of cell phone use, as independent variables, showed that female sex (odds ratio [OR], 2.06; 95% confidence interval [CI], 1.929-6.316; p = 0.0009) and ACT ≥ 20 (OR, 0.194; 95% CI, 0.039-0.967; p = 0.045) were associated with asthma and musculoskeletal pain (Nagelkerke R2 = 0.206). Conclusion: Musculoskeletal pain and musculoskeletal pain syndromes were lower in adolescents with asthma. Female sex was associated with musculoskeletal pain in asthmatic, whereas patients with asthma symptoms and well-controlled disease reported a lower prevalence of musculoskeletal pain.

Vascular Occlusion of the Quadriceps Muscle in Postural Control of Women with Patellofemoral Dysfunction / Oclusão Vascular do Músculo Quadríceps no Controle Postural de Mulheres com Disfunção Patelofemoral

Abstract The partial vascular occlusion (PVO) associated with exercises, proposed by the KAATSU Training method, has the objective of strengthening and muscle hypertrophy with low joint overload. Currently, PVO has been associated with exercises to strengthen then quadriceps, however it is not known about its influence on postural control or the possibility of imbalances during the performance of exercises. Objectives: To evaluate the effect of quadriceps vascular occlusion on postural control in women with patellofemoral pain syndrome (PFPS). Methods: The sample in this study was composed of four sedentary women, aged between 18 and 40 years, with a clinical diagnosis of patellofemoral dysfunction. Participants responded to the Visual Analog Pain Scale (VAS) and the Anterior Knee Pain Scale (AKPS). They were submitted to an evaluation of postural control over the force platform, by means of dynamic one-legged squat activity, with and without PVO. The variables of postural control analyzed were Area of pressure center (A-COP), Anteroposterior (AP) and medium-lateral (ML), Velocity AP and ML. Results: No significant differences were found for the variables of postural control analyzed when comparing the moments with and without peripheral vascular occlusion during single-legged squat activities. Conclusion: The single leg squat with vascular occlusion does not change the postural control of patients with PFPS with and without PVO, and that the method can be used for training these patients, without impairments related to postural control. (AU)

Resumo A oclusão vascular parcial (OVP) associada a exercícios, proposta pelo método KAATSU Training, tem como objetivo o fortalecimento e hipertrofia muscular com baixa sobrecarga articular. Atualmente, a OVP tem sido associada a exercícios de fortalecimento do quadríceps, porém não se sabe sobre sua influência no controle postural ou na possibilidade de desequilíbrios durante a execução dos exercícios. Objetivos: Avaliar o efeito da oclusão vascular do quadríceps no controle postural de mulheres com síndrome da dor patelofemoral (SDFP). Métodos: A amostra deste estudo foi composta por quatro mulheres sedentárias, com idade entre 18 e 40 anos, com diagnóstico clínico de disfunção femoropatelar. Os participantes responderam à Escala Visual Analógica de Dor (VAS) e à Escala de Dor Anterior no Joelho (AKPS). Elas foram submetidas à avaliação do controle postural sobre a plataforma de força, por meio da atividade de agachamento unipodal dinâmico, com e sem OVP. As variáveis de controle postural analisadas foram área do centro de pressão (A-COP), ântero-posterior (AP) e médio-lateral (ML), velocidade AP e ML. Resultados: Não foram encontradas diferenças significativas para as variáveis de controle postural analisadas na comparação dos momentos com e sem OVP durante o agachamento unipodal. Conclusão: O agachamento unipodal com OVP não alterou o controle postural de mulheres com SDFP, e o método pode ser utilizado para treinar esses pacientes, sem prejuízos relacionados ao controle postural. (AU)

Research Progress on Characteristics of Lower Limb Movement Patterns and Rehabilitation Treatment of Patellofemoral Pain Syndrome / 医用生物力学

Patellofemoral pain syndrome (PFPS) has been attracting more and more attention in the field of rehabilitation treatment due to its high incidence rate and low cure rate. Researches show that the abnormal anatomy, muscle activity changes due to pain and insufficient muscle strength in patients with PFPS can cause wrong movement patterns of lower limb joints, which will lead to aggravation of the disease and is not conducive to the rehabilitation of patients. Movement patterns of the hip, knee, ankle joints can be improved by exercise therapy, taping, neuromuscular training and joint orthosis, thus to reduce the pain. In this paper, the movement pattern characteristics of patients with PFPS and the corresponding rehabilitation treatment method were summarized, so as to provide references for the rehabilitation of PFPS.

Fortalecimiento muscular de cadera y rodilla en el síndrome doloroso patelofemoral: Revisión sistemática y metaanálisis / Hip and knee muscle strengthening in patellofemoral pain syndrome: Systematic review and meta-analysis / Fortalecimento muscular do quadril e joelho na síndrome da dor patelofemoral: revisão sistemática e meta-análise

El síndrome doloroso patelofemoral (SDPF) es una condición musculoesquelética frecuente que se manifiesta con dolor retro y peripatelar. El fortalecimiento muscular de cadera y rodilla (FCR) ha sido propuesto como un tratamiento apropiado para el SDPF. Es precisa una revisión que compare los resultados del FCR con otras intervenciones utilizando evidencia científica actual. OBJETIVO: evaluar la efectividad del FCR en pacientes con SDPF. MATERIALES Y MÉTODOS: la revisión sistemática (RS) y metaanálisis (MA) siguieron las directrices PRISMA. El cribaje y selección de estudios se realizó mediante el programa Rayyan. Nueve artículos fueron incluidos y evaluados con la escala PEDro y la herramienta Riesgo de Sesgo de Cochrane. El MA se realizó en la aplicación Jamovi. Las variables utilizadas fueron dolor, funcionalidad y fuerza muscular. RESULTADOS: el MA demostró que el FCR fue superior en la disminución del dolor (2.30;1.18, 3.42; 95%IC) (1.76; 0.70, 2.81; 95%IC) y el incremento de la funcionalidad (14.30 ;7.49, 21.11; 95%IC) (8.66 ;3.08, 14.23; 95%IC) comparado con los grupos sin intervención (NI) y los del fortalecimiento de rodilla (FR), respectivamente; mientras que la adición de intervenciones al fortalecimiento de cadera y rodilla (FCR+) demostró mayores beneficios en la funcionalidad (-5.71; -8.32, -3.10; 95%IC) al compararse con el FCR. Así mismo, el análisis cualitativo de la variable fuerza muscular estableció que el FCR obtuvo mejores resultados que los grupos de FR y FCR+ ejercicios de control motor. CONCLUSIONES: el FCR es una intervención efectiva en la reducción del dolor, el incremento de la funcionalidad y fuerza muscular en pacientes con SDPF.

Patellofemoral pain syndrome (PFPS) is a common musculoskeletal condition that manifests with retro- and peripatellar pain. Hip and knee muscle strengthening (HKS) has been proposed as an appropriate treatment for PFPS. A review comparing the results of HKS with other interventions using current scientific evidence is needed. OBJECTIVE: to evaluate the effectiveness of HKS in patients with PFPS. MATERIALS AND METHODS: the systematic review (SR) and meta-analysis (MA) followed PRISMA guidelines. Screening and selection of studies was performed using the Rayyan program. Nine articles were included and evaluated with the PEDro scale and the Cochrane Risk of Bias tool. The MA was performed in the Jamovi application. The variables used were pain, functionality and muscle strength. RESULTS: the MA showed that the HKS was superior in decreasing pain (2.30; 1.18, 3.42; 95%CI) (1.76; 0.70, 2.81; 95%CI) and increasing functionality (14.30; 7.49, 21.11; 95%CI) (8.66; 3.08, 14.23; 95%CI) compared to the no intervention (NI) and knee strengthening (KS) groups, respectively; while the addition of interventions to hip and knee strengthening (HKS+) demonstrated greater benefits in functionality (-5.71; -8.32, -3.10; 95%CI) when compared to HKS. Likewise, qualitative analysis of the muscle strength variable established that the HKS obtained better results than the KS and HKS+ motor control exercises groups. CONCLUSIONS: HKS is an effective intervention in reducing pain, increasing functionality and muscle strength in patients with PFPS.

A síndrome da dor patelofemoral (SDPF) é uma condição musculoesquelética comum que se manifesta com dor retro e peripatelar. O fortalecimento dos músculos do quadril e joelho (FQJ) foi proposto como um tratamento adequado para o SDPF. É necessária uma revisão comparando os resultados da FQJ com outras intervenções utilizando as evidências científicas atuais. OBJETIVO: avaliar a eficácia da FQJ em pacientes com SDPF. MATERIAIS E MÉTODOS: a revisão sistemática (RS) e a meta-análise (MA) seguiram as diretrizes do PRISMA. A triagem e seleção dos estudos foi realizada utilizando o software Rayyan. Nove artigos foram incluídos e avaliados utilizando a escala PEDro e a ferramenta Cochrane Risk of Bias. O MA foi realizado na aplicação Jamovi. As variáveis utilizadas foram dor, funcionalidade e força muscular. RESULTADOS: o MA mostrou que o FQJ foi superior em diminuição da dor (2,30; 1,18, 3,42; 95%CI) (1,76; 0,70, 2,81; 95%CI) e aumento da função (14,30; 7,49, 21,11; 95%CI) (8,66; 3,08, 14.23; 95%CI) em comparação com os grupos sem intervenção (NI) e de fortalecimento do joelho (FJ), respectivamente; enquanto a adição de intervenções de fortalecimento do quadril e joelho (FQJ+) demonstrou maiores benefícios em função (-5,71; -8,32, -3,10; 95%CI) quando comparado com o FQJ. Da mesma forma, a análise qualitativa da variável força muscular estabeleceu que o FQJ teve melhor desempenho do que os grupos FJ e FQJ+ exercícios de controlo do motor. CONCLUSÕES: o FQJ é uma intervenção eficaz na redução da dor, aumentando a funcionalidade e a força muscular em pacientes com SDPF.

SEBT in individuals with patellofemoral pain: an integrative review / SEBT em indivíduos com dor patelofemoral: uma revisão integrativa

Abstract Introduction: Decreased postural stability can be observed in individuals with patellofemoral pain (PP). The Star Excursion Balance Test (SEBT) is widely used to assess deficits that need to be improved, with different application methods and result presentation formats. Objective: To map SEBT use in individuals with PP, characterizing the studies that applied it to identify different application methods and result presentation formats. Methods: The review included randomized and non-randomized clinical trials, cross-sectional, case-control and cohort studies. Searches were performed in Pubmed and SciElo databases. Data extracted from eligible studies were divided into categories: (I) study characterization (II) SEBT application methods and result presentation formats. Results: A total of 177 studies were identified in the databases, 13 of which were selected. There are a growing number of new studies that assess the dynamic postural control of individuals with PP using the SEBT, and a variety of test application and result presentation formats. Conclusion: The SEBT is a useful, easy-to-apply test that identifies changes in dynamic postural control in individuals with PP. Different application and result presentation formats are in accordance with the literature, but it is recommended that future studies apply the protocols most widely used in previous studies that exhibit a low risk of bias, in order to improve repeatability and comparisons between studies.

Resumo Introdução: A diminuição da estabilidade postural pode ser observada em indivíduos com dor patelofemoral (DP). O Star Excursion Balance Test (SEBT) é um teste amplamente utilizado para a avaliação de déficits que precisam ser melhorados e também pode apresentar diferentes maneiras de aplicabilidade e apresentação dos resultados obtidos. Objetivo: Mapear a utilização do SEBT em indivíduos com DP, caracterizando os estudos que utilizaram o teste, de maneira a identificar diferentes formas de aplicabilidade e apresentação dos resultados. Métodos: A presente revisão incluiu ensaios clínicos randomizados e não randomizados, estudos transversais, caso-controle e estudos de coorte. As buscas foram realizadas nas bases de dados Pubmed e SciELO. Dados extraídos dos estudos elegíveis foram designados em categorias: (I) caracterização dos estudos, (II) formas de aplicação do SEBT e apresentação de resultados. Resultados: Foram identificados um total de 177 registros nas bases de dados analisadas e 13 destes foram selecionados. Existe um número crescente de novos estudos que buscam avaliar o controle postural dinâmico de indivíduos com DP utilizando o SEBT, sendo que existe uma variabilidade na aplicabilidade do teste e também na apresentação dos resultados. Conclusão: O SEBT é um teste útil, de fácil aplicabilidade e que identifica alterações do controle postural dinâmico em indivíduos com DP. Diferentes formas de aplicação e apresentação dos resultados do teste estão de acordo com a literatura, porém recomenda-se que estudos futuros utilizem os protocolos mais utilizados em estudos prévios que apresentem baixo risco de viés, para que seja possível melhorar a repetibilidade e as comparações entre estudos.

Current Concepts in the Management of Patellofemoral Pain Syndrome / Conceptos Actuales en el Manejo del Síndrome de Dolor Patelofemoral

Introduction Patellofemoral pain syndrome (PFPS) is one of the leading causes of knee pain, manifesting itself during daily life activities. This study presents a review on PFPS treatment modalities. Materials and methods State of the art review on the treatment of PFPS with grades of recommendation. Active and passive conservative interventions are reviewed, as well as surgical alternatives. Results Hip and lower-limb muscle strengthening and stretching are active interventions that provide long-lasting benefits. Passive interventions include patellofemoral joint bracing, kinesiotaping and foot orthoses, and are considered useful coadjuvants to active interventions, with quick relief for patients but usually in the short term. Surgical treatment is only recommended in a small subset of patients with specific anatomic abnormalities in the patellofemoral joint. Discussion Conservative treatment remains as the mainstream in the management of patellofemoral pain syndrome.

Introducción El síndrome de dolor patelofemoral (SDPF) es una de las principales causas de dolor de rodilla y se presenta con actividades diarias de la vida cotidiana. Este estudio presenta una revisión de la literatura acerca de las modalidades de tratamiento actual para el SDPF. Materiales y métodos Revisión estado del arte acerca del tratamiento del SDPF con grados de recomendación según la evidencia. Se revisan las intervenciones conservadoras activas y pasivas, así mismo las alternativas quirúrgicas. Resultados El fortalecimiento de los músculos de la cadera y del miembro inferior, así como el estiramiento, son intervenciones activas que ofrecen beneficios en el largo plazo para el SDPF. Las intervenciones pasivas como las rodilleras, el kinesiotaping y las ortesis para los pies, ofrecen alivio rápido pero de corta duración. El tratamiento quirúrgico solamente se recomienda en un subgrupo de pacientes que no han respondido a otros tratamientos y que tienen ciertas anormalidades anatómicas específicas que alteran la articulación patelofemoral. Discusión El tratamiento conservador continúa siendo la piedra angular en el tratamiento del síndrome de dolor patelofemoral